Comparative evaluation of the Roche Cobas AmpliPrep/Cobas TaqMan HIV-1 version 2 test using the TaqMan 48 analyzer and the Abbott RealTime HIV-1 assay

使用 TaqMan 48 分析仪对罗氏 Cobas AmpliPrep/Cobas TaqMan HIV-1 版本 2 检测和雅培 RealTime HIV-1 检测进行比较评估

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Abstract

Acceptable precision was achieved in a comparison study of the Abbott RealTime (RT) and Roche CAP/CTM-48 V2 HIV-1 assays, but viral load quantification was under- and overestimated, respectively, compared to the 2nd HIV-1 WHO International Standard. The same quantification patterns were observed for patient cohorts from Africa and the United States.

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