Abstract
Severe acute respiratory syndrome coronavirus 2 infection has resulted in a pandemic, the disease manifests itself as various conditions ranging from respiratory disorders to exacerbated inflammatory responses. The management in some cases involves immediate care in an intensive setup with the administration of various antibiotics and steroids which has resulted in the imposition of risk factors and growth of fulminant fungal infection. The present article addresses two such cases which presented with osteomyelitis secondary to mucormycosis in patients who had more than one episode of COVID-19 infection. The upsurge of existing manifestation and development of opportunistic infections has to be considered in patients who are suffering or recovering from COVID-19. The COVID-19 scenario brings up a possibility of many bacterial and fungal infections in its aftermath. This article brings out two such opportunistic aggressive fungal infections and comprehensive management of the same.