Phase II study of bleomycin, dacarbazine (DTIC) and vindesine in disseminated malignant melanoma

博来霉素、达卡巴嗪 (DTIC) 和长春地辛治疗播散性恶性黑色素瘤的 II 期研究

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Abstract

Thirty-one patients with disseminated malignant melanoma were treated with a combination chemotherapy of bleomycin, dacarbazine and vindesine. Five complete responses, and five partial remissions occurred. One patient survived for over 2 years without evidence of disease. This combination of drugs may give better results, as far as complete recovery and long-term survival are concerned, than single-agent therapy with dacarbazine.

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