Integrated Human Immunodeficiency Virus Type 1 Sequence in J-Lat 10.6

J-Lat 10.6 中的整合人类免疫缺陷病毒 1 型序列

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作者:Cheng-Han Chung #, Anthony R Mele #, Alexander G Allen, Robert Costello, Will Dampier, Michael R Nonnemacher, Brian Wigdahl

Abstract

The full length of HIV/R7/E-/GFP integrated in the J-Lat 10.6 cell line was sequenced in this study. The single copy of the integrated virus, including the breakpoints from the human chromosome to the provirus, was amplified by two separate PCRs. A 10,200-bp genome sequence was acquired, analyzed, and deposited in GenBank.

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