Altered Pattern of Immunoglobulin A-Targeted Microbiota in Inflammatory Bowel Disease After Fecal Transplantation
粪便移植后炎症性肠病中免疫球蛋白 A 靶向微生物群模式的改变
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作者:Wen-Qi Huang, Hong-Li Huang, Wu Peng, Yan-Di Liu, You-Lian Zhou, Hao-Ming Xu, Liang-Jie Zhang, Chong Zhao, Yu-Qiang Nie
Methods
gastroscopy spraying and colonic transendoscopic enteral tubing (TET). Then, we established an acute dextran sulfate sodium (DSS)-induced mouse model to explore whether FMT intervention would impact IgA/G memory B cell in the intestine. We found that after FMT, both IgA/G memory B cell and the percentage of IgA/G-targeted bacteria were restored to normal levels in DSS mice.
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