Genome Analysis of Klebsiella oxytoca Complex for Antimicrobial Resistance and Virulence Genes

对产酸克雷伯菌复合群的抗菌素耐药性和毒力基因进行基因组分析

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Abstract

Klebsiella oxytoca complex comprises nine closely related species causing human infections. We curated genomes labeled Klebsiella (n = 14,256) in GenBank and identified 588 belonging to the complex, which were examined for precise species, sequence types, K- and O-antigen types, and virulence and antimicrobial resistance genes. The complex and Klebsiella pneumoniae share many K- and O-antigen types. Of the complex, K. oxytoca and Klebsiella michiganensis appear to carry more virulence genes and be more commonly associated with human infections.

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