Abstract
AIM: In recent years, we have seen a considerable increase in the relevance of nanostructures for the safe delivery of therapeutic agents and their capacity as an immunomodulatory tool. MATERIALS AND METHODS: Potential clinical applications related to their unique structural properties have been described in the evolving landscape of immunotherapy. RESULTS: This review briefly summarizes the evidence for the role of nanoparticles in regulating the immune response. CONCLUSIONS: Their main features to highlight how to provide an innovative means of biomedical application to oncology research.