A hybrid approach for identifying drug repurposing candidates and their mechanisms: An interview with Vanessa Lage-Rupprecht and two co-authors

一种用于识别药物再利用候选物及其作用机制的混合方法:对 Vanessa Lage-Rupprecht 和两位合作者的采访

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Abstract

Senior researcher Vanessa Lage-Rupprecht and two collaborators talk about what data science means to them and illustrate how they managed to create a data and lab coexistence in their drug-repurposing project, which was recently published in Patterns. In this article, they have developed a drug-target-mechanism-oriented data model, Human Brain PHARMACOME, and have presented it as a resource to the community.

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