Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults

糖尿病状况对老年人三价灭活流感疫苗免疫原性的影响

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Abstract

Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50-80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold-increases in antibody titer occurred among participants with lower pre-vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status.

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