Abstract
Citrus juices represent a nutrient-dense beverage due to the remarkable balance in their bioactive compounds (vitamins, minerals, dietary fibers, and phytochemicals such as flavonoids and carotenoids). This review aims to examine the nutritional quality and the health benefits of citrus juice consumption linked to the world diversity of citrus fruits. This work provides heterogenous data found on the main citrus bioactive compounds, especially carotenoids and flavonoids, which are difficult to correlate to particular geographic areas. Through an example of study, this work addresses the question of how and to what extent the content of citrus bioactive compounds is linked to the health benefits observed in humans. We explore through the more recent human clinical trials, the health effects of consuming citrus fruit or taking dietary supplements of bioactive compounds to prevent the exponential increase of world chronic diseases (type 2 diabetes, cardiovascular diseases, and obesity) and discuss the effects of dose. Finally, even if the data highlight the importance of geographical origin in accumulation of carotenoids or flavonoids from different Citrus species, the difference of content in front of the complex human metabolism of their absorption has lesser consequences for health than the fact of consuming citrus or not. The citrus health effect results in a synergistic action of numerous phytochemicals whose targeted health benefits vary depending more on the diversity of Citrus species than their geographic origin. Therefore, the use of the diversity of Citrus species could be an interesting approach to providing functional food.