Nonsurgical Management of Drug-induced Gingival Enlargement in a Young Adolescent with Chronic Kidney Disease: A Case Report

慢性肾病青少年药物性牙龈增生的非手术治疗:病例报告

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Abstract

Drug-induced gingival enlargement represents a well-documented adverse effect of medications utilized in treating systemic conditions. This case reports a 13-year-old female with chronic kidney disease and hypertension who was under the medication of atenolol and amlodipine for 5 years. Despite well-controlled blood pressure, the child developed a gingival enlargement, which is a documented side effect of amlodipine. The management included counseling, oral hygiene maintenance, full-arch scaling, and transition to alternate antihypertensive clonidine; the patient was reverted back to amlodipine after 1 month due to inadequate blood pressure control with clonidine. The patient exhibited no recurrence of gingival enlargement at the 3-year follow-up. This case highlights the importance of interdisciplinary management of drug-induced gingival enlargement and good oral hygiene measures to prevent gingival enlargement in calcium channel blocker intake. CLINICAL SIGNIFICANCE: Children who require medication of calcium channel blockers should be consulted with a pediatric dentist prior to commencement of drugs for instructions regarding importance of oral hygiene technique and scaling. Poor oral hygiene causes inflammation, which further acts as a risk factor for gingival growth. HOW TO CITE THIS ARTICLE: Tamchos R, Rathod P, Kapur A, et al. Non-surgical Management of Drug-induced Gingival Enlargement in a Young Adolescent with Chronic Kidney Disease: A Case Report. Int J Clin Pediatr Dent 2025;18(9):1164-1167.

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