SmI(2)/Sm-Induced Reductive Silacyclization of Alkene/Diene Derivatives Using Dichlorosilanes or 1,2-Dichlorodisilanes via Reductive Radical-Polar Crossover

利用二氯硅烷或1,2-二氯二硅烷,通过还原自由基-极性交叉反应,实现SmI(2)/Sm诱导的烯烃/二烯衍生物的还原硅环化反应

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Abstract

The development of efficient strategies for constructing cyclic organosilicon frameworks is considered of great importance because of their structural diversity and synthetic utility. Herein, we report a SmI(2)/Sm-mediated silacyclization of unsaturated organic compounds with readily available dichlorosilanes and -disilanes, enabling convenient access to 4-7-membered silacyclic compounds. Mechanistic investigations indicate that the reaction involves silyl radical intermediates and proceeds via a reductive radical-polar crossover (RRPCO) pathway. The present findings showcase the broad potential of Sm reagents in Si─C bond formation, providing a versatile strategy for constructing diverse silicon-containing frameworks.

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