Pancreatic Tumor-Derived Extracellular Vesicles Stimulate Schwann Cell Phenotype Indicative of Perineural Invasion via IL-8 Signaling
胰腺肿瘤衍生的细胞外囊泡通过 IL-8 信号刺激雪旺细胞表型，提示神经周围侵袭
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作者：Emory Gregory, Isabel Powers, Azemat Jamshidi-Parsian, Robert Griffin, Younghye Song
| 期刊： | bioRxiv | 影响因子： | |
| 时间： | 2023 | 起止号： | 2023 Jun 28:2023.06.26.546629. |
| doi： | 10.1101/2023.06.26.546629 | 研究方向： | 代谢、信号转导、神经、肿瘤 |
| 疾病类型： | 胰腺癌 | 细胞类型： | 其它细胞 |
| 信号通路： | Neuroscience | |
Significance
Identifying pancreatic tumor extracellular vesicles as key players in Schwann cell activation and perineural invasion by way of IL-8 will educate for more specialized and effective targets for an under-valued disease.
Statement of significance
Identifying pancreatic tumor extracellular vesicles as key players in Schwann cell activation and perineural invasion by way of IL-8 will educate for more specialized and effective targets for an under-valued disease.
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