A Case of Lung Cancer Unexpectedly Detected with (99m) Tc (V)-DMSA Whole-Body/SPECT Imaging

一例利用 (99m)Tc(V)-DMSA 全身/SPECT 显像意外发现的肺癌病例

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Abstract

In terms of cancer-related deaths, lung cancer is the most common type. To prevent this malignant and dangerous disease from progressing, early and differential diagnoses are very critical. A combination of dimercaptosuccinic acid and pentavalent (99m) Tc under alkaline conditions, (99m) Tc (V)-DMSA, can be used for malignant tumors' early diagnosis and prognosis. The (99m) Tc (V)-DMSA radiotracer is most commonly used for follow-up of medullary thyroid cancer metastases, but it is also successful in lung cancer and other malignancies. In this case, a 65-year-old woman with a recent history of nonproductive cough and mild dyspnea and suspicious small masses of lungs in computed tomography was selected for imaging with (99m) Tc (V)-DMSA to evaluate the condition of radiotracer uptake in the lung masses. The whole-body and single-photon emission computed tomography imaging with semiquantitative analysis showed abnormal uptakes in the lesions and the patient underwent to transbronchial biopsy and bronchial washing cytology that confirmed non-small cell lung cancer.

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