Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome

患有肾小管间质性肾炎和葡萄膜炎综合征的儿童发生急性肉芽肿性虹膜睫状体炎

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Abstract

BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months. CONCLUSIONS: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis.

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