Neutrophil extracellular traps in acute chorioamnionitis: A mechanism of host defense

急性绒毛膜羊膜炎中的中性粒细胞细胞外诱捕网:宿主防御机制

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作者:Nardhy Gomez-Lopez, Roberto Romero, Yaozhu Leng, Valeria Garcia-Flores, Yi Xu, Derek Miller, Sonia S Hassan

Conclusion

Neutrophil extracellular traps are abundant in the chorioamniotic membranes from women who underwent spontaneous term or preterm labor with acute chorioamnionitis. These findings suggest that chorioamniotic neutrophils can form NETs as a mechanism of host defense against infection or danger signals.

Results

Neutrophil extracellular traps were abundant in the chorioamniotic membranes from women who underwent spontaneous term or preterm labor with acute chorioamnionitis. NETs were rarely found, or not visualized at all, in the chorioamniotic membranes from women who delivered at term or preterm with or without labor in the absence of acute chorioamnionitis.

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