First detection of the mcr-1 colistin resistance gene in Escherichia coli from a patient with urinary tract infection in Myanmar

缅甸一名尿路感染患者的大肠杆菌中首次检测到mcr-1粘菌素耐药基因

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Abstract

Colistin-resistance gene mcr-1 was detected in an Escherichia coli sample among 442 clinical isolates collected in a tertiary-care hospital in Yangon, Myanmar, in 2018. This isolate was classified into phylogroup A-ST23 complex and harboured bla (CTX-M-15) and bla (TEM-1), associated with multiple mutations in quinolone-resistance-determining regions in gyrA and parC.

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