Transmission of two distinct HIV type 1 strains to an individual that were harbored for many years by another

两种不同的 HIV-1 型毒株被传播给同一人,这两种毒株此前已由另一人携带多年。

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Abstract

The concept of transmission bottlenecks in HIV-1 infection is well established. Coinfections and superinfections have been increasingly documented and provide a founding cause for the expansion of viral diversity through recombination. It is still relatively unclear how HIV-1 will propagate and evolve in individuals infected with more than one viral strain. Here we report on the parallel transmission of genetically distant viral strains cocirculating in one individual over many years to a single recipient.

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