[Dual Roles of Neutrophil Extracellular Traps in Lung Cancer: 
Mechanism Exploration and Therapeutic Prospects]

【中性粒细胞胞外陷阱在肺癌中的双重作用:机制探索与治疗前景】

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Abstract

Lung cancer is one of the most common and lethal malignancies in China. In the context of the tumor microenvironment, neutrophil extracellular traps (NETs) released by neutrophils exert a profound impact on the occurrence and progression of lung cancer. Although the exact mechanisms by which NETs promote tumor growth have not been fully elucidated, existing research has revealed their multiple roles in tumor growth, invasion, metastasis, and cancer-related thrombosis. This article will review the molecular biology mechanisms and research progress of NETs in lung cancer based on recent studies.
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