Mechanical Properties and Biocompatibility of 3D Printing Acrylic Material with Bioactive Components

含生物活性成分的3D打印丙烯酸材料的力学性能和生物相容性

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Abstract

The aim of this study was to create a 3D printing material with bioactive properties that potentially could be used for a transparent removable orthodontic appliance. MATERIALS AND METHODS: To acrylic monomers, four bioactive glasses at 10% concentration were added, which release Ca, P, Si and F ions. The materials were printed on a 3D printer and tested for flexural strength (24 h and 30 days), sorption and solubility (7 days), ion release to artificial saliva pH = 4 and 7 (42 days) and cytotoxicity in the human fibroblast model. The released ions were determined by plasma spectrometry (Ca, P and Si ions) and ion-selective electrode (F measurement)s. RESULTS: The material obtained released Ca(2+) and PO(4)(3-) ions for a period of 42 days when using glass Biomin C at pH 4. The flexural strength depended on the direction in which the sample was printed relative to the 3D printer platform. Vertically printed samples had a resistance greater than 20%. The 10% Biomin C samples post-cured for 30 min with light had a survival rate of the cells after 72 h of 85%. CONCLUSIONS: Material for 3D printing with bioactive glass in its composition, which releases ions, can be used in the production of orthodontic aligners.

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