Acute Torticollis Reaction Following Metoclopramide Use in a Pediatric Patient: A Comprehensive Case Report and Appraisal of Current Knowledge

儿童患者使用甲氧氯普胺后发生急性斜颈反应:病例报告及现有知识评估

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Abstract

Dopamine receptor antagonists like metoclopramide are frequently used in a variety of clinical contexts to treat gastrointestinal disorders and control nausea and vomiting. However, it is associated with a high incidence of extrapyramidal side effects (EPS) in children, including dystonic movements and torticollis. This is the instance of a 9-year-old girl who developed abnormal movements of the neck and tongue, along with torticollis, within 48 hours of receiving intravenous metoclopramide for gastroenteritis. The metoclopramide therapy was discontinued, and supportive measures, including diphenhydramine, were initiated, resulting in the resolution of symptoms. This case highlights the importance of recognizing and managing metoclopramide-induced EPS in pediatric patients.

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