A snapshot of ABO, RH, and JK blood group systems in modern Ireland

现代爱尔兰的 ABO、RH 和 JK 血型系统概况

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作者:Anne Browne, Anthony Kinsella, Moira Keogh, Kieran Morris, Stephen Field

Background

Ireland's population is constantly increasing and becoming more diverse, this has potential implications for the IBTS to provide blood with extended phenotypes for certain cohorts of patients. Materials and

Conclusion

The observed frequencies for the relevant BGSs remained relatively unchanged to the prevalence values expected; however, statistically significant differences between the 2015 study and some of the previous studies were found for ABO distribution. 14.24% of the first time donors were born outside Ireland and statistically significant differences (P-value < 0.001) were noted for aspects of the ABO and Rh phenotype distribution for the Irish born donors (BiI) vs those born outside Ireland (BoI).

Methods

All first time blood donors had relevant testing performed in the Automated Donor Grouping (ADG) laboratory using the Beckman Coulter PK7300 analyzer with appropriate antisera by validated methods. All pertinent information and test

Results

The number of donors tested was 3427. ABO phenotype: A: 29.82%, B: 12.02%, O: 54.95% and A,B: 3.21%. RHD: 82.26%. RHCE: R1R1: 17.62%, R2R2: 2.89%, R1R2: 13.95%, R1r: 33.35%, R2r: 13.07%, Ror: 1.25%, R1RZ: 0.06%, R2RZ: 0.06%, r'r: 0.55%, r″r: 0.53%, rr: 16.66%. Kidd phenotype: Jk(a + b+): 49.63%, Jk(a-b+): 23.34%, Jk(a + b-): 27.02%.

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