Pelvic lipomatosis with cystitis glandularis managed with cyclooxygenase-2 inhibitor: A case report

环氧合酶-2 抑制剂治疗盆腔脂肪瘤并发腺性膀胱炎:一例病例报告

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作者:Li-Cai Mo, Song-Zhe Piao, Hai-Hong Zheng, Tao Hong, Qin Feng, Mang Ke

Background

Pelvic lipomatosis (PL) is a rare benign condition with characteristic overgrowth of histologically benign fat and invasion and compression of pelvic organs, often leading to non-specific lower urinary tract symptoms (LUTS). Approximately 40% of patients with PL have cystitis glandularis (CG). The cause of PL combined with CG is poorly understood, and there is currently no effective treatment. Refractory CG with upper urinary tract obstruction even requires partial or radical bladder resection. Case summary: In this case, a patient suffering from PL with CG was treated by transurethral resection of bladder tumour (TUR-BT) and oral administration of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor. The LUTS were alleviated, and the cystoscopy

Conclusion

We report for the first time that celecoxib may be an effective treatment strategy for PL combined with refractory CG.

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