Determination of the beam quality correction factor kQmsr for the PTW Semiflex 3D ionization chamber for the reference dosimetry at ZAP-X

确定 ZAP-X 参考剂量测定中 PTW Semiflex 3D 电离室的束流质量校正因子 kQmsr。

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Abstract

PURPOSE: The self-shielding radiosurgery system ZAP-X consists of a 3 MV linear accelerator and eight round collimators. For this system, it is a common practice to perform the reference dosimetry using the largest 25 mm diameter collimator at a source-to-axis distance (SAD) of 45 cm with the PTW Semiflex3D chamber placed at a measurement depth of 7 mm in water. Existing dosimetry protocols do not provide correction for these measurement conditions. Therefore, Monte Carlo simulations were performed to quantify the associated beam quality correction factor kQmsr,Qreffmsr,fref . METHODS: The kQmsr,Qreffmsr,fref of the Semiflex3D chamber was computed from the ratio of the absorbed doses in a water voxel and in the sensitive air volume of the chamber simulated using a (60)Co spectrum as the calibration beam quality (Q(ref)) and the spectrum of the ZAP-X 3 MV photon beam (Q(msr)). kQmsr,Qreffmsr,fref was computed as a function of measurement depth from 4 to 50 mm. Furthermore, detailed simulations were performed to determine the individual chamber's perturbation correction factors by modifying the chamber's model step-wise. RESULTS: All perturbation correction factors, except S(w,air) ⋅P(fl), show depth-dependent behavior up to a depth of 15 mm. In particular, the volume-averaging P(vol) and density P(dens) perturbation correction factors and, consequently, the resulting gradient perturbation correction factor P(gr )= P(vol)∙P(dens) increase with decreasing measurement depth. Therefore, kQmsr,Qreffmsr,fref is larger than unity, amounting to 1.0104 ±  0.0072 at 7 mm measurement depth. At larger depths (> 15 mm), the kQmsr,Qreffmsr,fref = 0.9964  ±  0.0025 can be considered as constant. CONCLUSION: At small measurement depths, kQmsr,Qreffmsr,fref was found to be depth-dependent with values larger than unity due to the gradient-related perturbation factors. Therefore, the uncertainty related to the chamber's positioning can be reduced by performing the reference dosimetry at ZAP-X at depths larger than 15 mm, where kQmsr,Qreffmsr,fref can be regarded as depth independent.

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