Electron beam therapy at extended source-to-surface distance: a Monte Carlo investigation

电子束治疗在较长源皮距下的疗效:蒙特卡罗模拟研究

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Abstract

Electron-beam therapy is used to treat superficial tumors at a standard 100 cm source-to-surface distance (SSD). However, certain clinical situations require the use of an extended SSD. In the present study, Monte Carlo methods were used to investigate clinical electron beams, at standard and non-standard SSDs, from a Siemens Oncor Avant Garde (Siemens Healthcare, Erlangen, Germany) linear accelerator (LINAC). The LINAC treatment head was modeled in BEAMnrc for electron fields 5 cm in diameter and 10 x 10 cm, 15 x 15 cm, and 20 x 20 cm; for 6 MeV, 9 MeV, and 12 MeV; and for 100 cm, 110 cm, and 120 cm SSD. The DOSXYZnrc code was used to calculate extended SSD factors and dose contributions from various parts of the treatment head. The main effects of extended SSD on water phantom dose distributions were verified by Monte Carlo methods. Monte Carlo-calculated and measured extended SSD factors showed an average difference of +/-1.8%. For the field 5 cm in diameter, the relative output at extended SSD declined more rapidly than it did for the larger fields. An investigation of output contributions showed this decline was mainly a result of a rapid loss of scatter dose reaching the d max point from the lower scrapers of the electron applicator. The field 5 cm in diameter showed a reduction in dose contributions; the larger fields generally showed an increased contribution from the scrapers with increase in SSD. Angular distributions of applicator-scattered electrons have shown a large number of acute-angle electron tracks contributing to the output for larger field sizes, explaining the shallow output reduction.

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