In vitro effects of albendazole sulfoxide and praziquantel against Taenia solium and Taenia crassiceps cysts

阿苯达唑亚砜和吡喹酮对猪带绦虫和粗颈带绦虫包囊的体外作用

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作者：Palomares,Francisca,Palencia,Guadalupe,Pérez,Rodolfo,González-Esquivel,Dinora,Castro,Nelly,Cook,Helgi Jung
期刊：Antimicrobial Agents and Chemotherapy影响因子：4.500
时间：2004起止号：2004 Jun;48(6):2302-4
doi：10.1128/AAC.48.6.2302-2304.2004

Abstract

We investigated the minimum exposure times of prazicuantel (PZQ) and albendazole sulfoxide (ABZSO) required for their activities against Taenia cysts in vitro as well as the 50 and 99% effective concentrations. The results showed that although the effects of both drugs are time and concentration dependent, ABZSO acts much slower and is less potent than PZQ.

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