Spinal myxopapillary ependymoma with anaplastic features: A case report and review of the literature

脊髓粘液乳头状室管膜瘤伴间变性特征:病例报告及文献复习

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Abstract

BACKGROUND: Spinal myxopapillary ependymomas (MPEs) are a rare subtype of ependymomas that typically arise in the conus medullaris, cauda equina, and filum terminale, most commonly affecting adults aged 30-50 years and usually located in the lumbosacral spine. Anaplastic MPEs are an even rarer, more aggressive variant that often present at a younger age than conventional MPEs. CASE DESCRIPTION: We report a 20-month-old male who presented with a two-week history of abnormal gait and neck stiffness and was diagnosed with anaplastic MPE. CONCLUSION: This case adds to the limited pediatric literature on anaplastic MPE and underscores the importance of early recognition, thorough histopathological evaluation, and long-term follow-up.

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