Expression of Concern: Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression

关注事项：Notch1信号通路通过抑制Akt/Hdm2介导的p53降解和上调p53依赖的DR5表达，增强人肝细胞癌细胞对肿瘤坏死因子相关凋亡诱导配体（TRAIL）诱导的细胞凋亡的敏感性。