Non-inferiority of minimally invasive rotational cutting in granulomatous mastitis treatment: a comparative trial

微创旋转切开术治疗肉芽肿性乳腺炎的非劣效性:一项比较试验

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Abstract

Granulomatous mastitis (GM) poses challenges in diagnosis and treatment due to its similarities with other breast diseases like cancer. The comparative study evaluated the efficacy and safety of a vacuum-assisted biopsy device with minimally invasive excisions compared to traditional wide local excisions. The vacuum-assisted biopsy device technique offers benefits such as precise tissue removal, reduced damage to healthy tissue, shorter surgery and recovery times, and lower postoperative complication risks. The study found that the vacuum-assisted biopsy device had comparable efficacy to traditional wide local excision in treating GM with an overall effectiveness rate of 92.9% and a recurrence rate of 9.52%. The vacuum-assisted biopsy device group showed advantages in reduced hospitalization duration (2.83 days vs. 7.52 days), lower costs, and better cosmetic outcomes, with a 100% patient satisfaction rate compared to 80% in the control group. This study fills existing clinical evidence gaps regarding the effectiveness and safety of vacuum-assisted biopsy device in GM treatment. By providing evidence-based guidelines, it aims to assist clinicians in choosing the most appropriate treatment for GM patients, ultimately improving their quality of life and mental well-being. The research contributes valuable insights into GM therapy, potentially revolutionizing treatment approaches and enhancing patient outcomes.

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