Bronchoscopy-Guided Bronchial Blocker for Acute Right Pulmonary Artery Hemorrhage in an Infant With Berry Syndrome: A Case Report

支气管镜引导下支气管封堵器治疗贝瑞综合征患儿急性右肺动脉出血:病例报告

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Abstract

BACKGROUND Berry syndrome is a rare congenital cardiovascular disorder characterized by typical malformations (eg, right pulmonary artery [RPA] origin from the aorta, aortic arch interruption, and atrial septal defect), most of which require surgical correction in infancy or early childhood. CASE REPORT A 1-week-oldinfant presented with postnatal dyspnea, irregular respiration, and poor weight gain. A diagnosis of Berry syndrome was confirmed via transthoracic echocardiography and cardiac great-vessel computed tomography angiography. The infant first underwent successful initial surgery to correct the core heart malformations. Follow-up transthoracic echocardiography at 5 months of age revealed progressive RPA stenosis requiring staged interventional treatment. During preparation for stent deployment, the infant developed acute decompensation: oxygen saturation dropped sharply, and hemorrhagic tracheal secretions were observed, consistent with acute massive RPA hemorrhage. A multidisciplinary team (cardiac surgeons, anesthesiologists, and respiratory endoscopists) performed emergency intervention. Under bronchoscopic guidance, a 5-Fr bronchial blocker was inserted into the right main bronchus to occlude the bleeding site; the endotracheal tube was replaced; and bloody thrombi were removed via lavage, suction, and basket extraction. Post-procedure bronchoscopy confirmed patent left bronchi and no active RPA bleeding. The infant was extubated on post-intervention day 5 with stable hemodynamics and was discharged 2 weeks later with normal respiratory function. CONCLUSIONS This case represents the first successful application of bronchoscopy-guided bronchial blocker at our institution for control of acute massive RPA hemorrhage. For resuscitation of pediatric massive pulmonary artery hemorrhage, in addition to routine rescue measures, bronchoscopy-guided bronchial blocker placement offers an effective emergency strategy.

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