Evaluation of an Immunochromatographic Assay for Rapid Detection of Penicillin-Binding Protein 2a in Human and Animal Staphylococcus intermedius Group, Staphylococcus lugdunensis, and Staphylococcus schleiferi Clinical Isolates

评估免疫层析法快速检测人类和动物中间葡萄球菌群、路邓葡萄球菌和施来费葡萄球菌临床分离株中青霉素结合蛋白 2a 的效果

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作者:A R Arnold, C-A D Burnham, B A Ford, S D Lawhon, S K McAllister, D Lonsway, V Albrecht, R C Jerris, J K Rasheed, B Limbago, E M Burd, L F Westblade

Abstract

The performance of a rapid penicillin-binding protein 2a (PBP2a) detection assay, the Alere PBP2a culture colony test, was evaluated for identification of PBP2a-mediated beta-lactam resistance in human and animal clinical isolates of Staphylococcus intermedius group, Staphylococcus lugdunensis, and Staphylococcus schleiferi. The assay was sensitive and specific, with all PBP2a-negative and PBP2a-positive strains testing negative and positive, respectively.

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