Factors associated with depression and cognitive impairment after cerebral hemorrhage surgery

脑出血手术后抑郁和认知障碍的相关因素

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Abstract

This study aims to investigate various factors, such as hemorrhage locations, cognitive and emotional outcomes, to provide valuable information for clinical interventions and the management of mental disorder patients following surgical procedures. A total of 94 patients who underwent surgery were included, and their demographic information, encompassing surgical methods, pre- and post-surgical haemorrhagic data, Then mobility of limbs and psychological assessments were collected. At 2 weeks post-surgery, the HAMD score for the right Basal Ganglia Haemorrhage (BGH) group was significantly higher than that of the right Basal Ganglia Breaking into ventricular haemorrhage (BGBVH), ventricular infarction and haemorrhage (VIH), or cerebellar haemorrhage (CLH) groups (all P < 0.05). At 3 months, there was a significant difference in HAMD score between the high-risk right BGH and the low-risk VIH groups (P = 0.023). There was a correlation between functional independence measure (FMA), activities of daily living (ADL) and HAMD scores, as well as a linear relationship between Glasgow Coma Scale (GCS)/ADL scores and Mini-Mental State Examination (MMSE) scores, and a linear relationship between haemorrhage location, ADL score, and Montreal Cognitive Assessment (MoCA) scores. The primary factor contributing to depression in patients with intracerebral haemorrhage (ICH) is the decrease in ADL and FMA scores after surgery. Additionally, ADL, GCS, surgical methods and bleeding sites can affect the cognitive function of patients.

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