Abstract
OBJECTIVE: This study aimed to analyze the epidemiological, hematological, and oxidative stress profile of truck drivers. METHOD: It involved 63 drivers from the western border of a state in southern Brazil who completed a questionnaire, had vital signs and anthropometric evaluations, and provided blood samples. Hematological parameters, leukocytes, and oxidative damage to proteins and lipids were analyzed. RESULTS: A high prevalence of overweight and obesity was found among the drivers, with an increased risk of cardiovascular issues and hypertension. Obese drivers had higher monocyte counts, while those with normal weight had increased protein carbonylation levels. CONCLUSIONS: It is crucial to implement health interventions to prevent chronic diseases in truck drivers, given their high exposure to risk factors.