Prakriti phenotyping in Central Serous Retinopathy (CSR): case series on Ayurvedic therapeutic outcomes in Vata individuals

体质表型在中心性浆液性视网膜病变(CSR)中的应用:瓦塔体质个体阿育吠陀疗法疗效病例系列研究

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Abstract

BACKGROUND: Central Serous Retinopathy (CSR) is a retinal disorder characterized by serous detachment of the neurosensory retina, commonly associated with psychological stress and Type A personality traits. From an Ayurvedic perspective, these features correspond to Vata predominance, marked by hyperactivity, anxiety, and autonomic instability. Such individuals may be constitutionally predisposed to disorders of Vata imbalance, including retinal pathologies resembling Vataja Shopha. This case series explores therapeutic outcomes of Ayurvedic management in CSR among individuals with Vata Prakriti. CASE PRESENTATION: Three patients-two males (aged 65 and 46 years) and one female (aged 40 years), diagnosed with CSR and confirmed as Vata Prakriti through a standardized questionnaire, were treated with an identical Ayurvedic regimen comprising Ashwagandha tablets, Punarnavadi Kashaya, Tiktaka Ghrita, Kalyanaka Ghrita, and Triphala Churna. Local ocular therapies included Shiro Pichu with Brahmi Ghrita, Pratimarsha Nasya with Anu Taila, and Anjana Karma with Elaneer Kozhumbu. Lifestyle advice emphasized regular sleep, timely meals, guided meditation, and reduced screen exposure. All three patients demonstrated marked improvement in visual acuity and complete anatomical resolution of macular fluid on Optical Coherence Tomography within 4-17 months. No recurrence was observed over 1 year of follow-up. CONCLUSION: This case series highlights a possible association between CSR and Vata Prakriti. Vata pacifying and Rasayana based Ayurvedic interventions showed favorable visual and structural outcomes. Incorporating Prakriti phenotyping in ocular disease management may enhance personalized, integrative approaches to retinal disorders.

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