Abstract
OBJECTIVE: Exploring the application value of thromboelastography (TEG) and four coagulation indicators in the risk assessment of thromboembolism (TE) in cancer patients. METHODS: Retrospectively analyzed the clinical data of 160 cancer patients. Among them, 45 patients experienced thromboembolism (TE group) and 115 patients did not experience thromboembolism (non-TE group). We analyzed the levels of TEG and coagulation indicators in the two groups of patients and the risk factors for TE in cancer patients. RESULTS: The Angle and MA of the thromboembolic group were significantly higher than those of the non-TE group, whereas K and R were significantly lower than those of the non-TE group (P < 0.05). D-dimer (D-D) and fibrinogen (FIB) levels in the thromboembolic group were significantly higher than those in the non-TE group, while activated partial thromboplastin time (APTT), prothrombin time (PT), and platelet count (PLT) were significantly lower than those in the non-TE group (P < 0.05). Binary logistic regression analysis confirmed that angle, maximum amplitude (MA), K, R, D-D, APTT, PT, and PLT were all important influencing factors for the occurrence of TE in cancer patients (P < 0.05). CONCLUSIONS: TEG and coagulation index level detection have high application values in the risk assessment of TE in cancer patients.