In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

使用 echoPIV 体外性能评估颈动脉支架内的层流分布

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作者:Astrid M Hoving, Jason Voorneveld, Julia Mikhal, Johan G Bosch, Erik Groot Jebbink, Cornelis H Slump

Conclusions

Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.

Purpose

Detailed blood flow studies may contribute to improvements in carotid artery stenting. High-frame-rate contrast-enhanced ultrasound followed by particle image velocimetry (PIV), also called echoPIV, is a technique to study blood flow patterns in detail. The performance of echoPIV in presence of a stent has not yet been studied extensively. We compared the performance of echoPIV in stented and nonstented regions in an in vitro flow setup. Approach: A carotid artery stent was deployed in a vessel-mimicking phantom. High-frame-rate contrast-enhanced ultrasound images were acquired with various settings. Signal intensities of the contrast agent, velocity values, and flow profiles were calculated.

Results

The results showed decreased signal intensities and correlation coefficients inside the stent, however, PIV analysis in the stent still resulted in plausible flow vectors. Conclusions: Velocity values and laminar flow profiles can be measured in vitro in stented arteries using echoPIV.

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