The hidden risks of advancing age and concomitant ischemic heart disease after aortic valve replacement

主动脉瓣置换术后,高龄及合并缺血性心脏病带来的隐患

阅读:2

Abstract

BACKGROUND: Despite an increasing patient risk profile, in-hospital mortality after aortic valve replacement (AVR) has declined. HYPOTHESIS: Advanced age, concomitant coronary artery bypass grafting (CABG), and increasing comorbidity negatively affect outcomes after AVR and do so particularly in the early months after hospital discharge, where results compare much less favorably with mortality during the first 30 days. METHODS: The study population consisted of all patients undergoing elective AVR by a single surgeon, with and without CABG, in the decade of 2000-2009. Age, logistic EuroSCORE, diabetes, type of operation, and 30-day and 1-year mortality were recorded. RESULTS: One hundred ninety-one patients underwent isolated AVR; 133 underwent AVR + CABG. The average age increased by 5.7 years, octogenarians by 50%, logistic EuroSCORE by 18%, and the proportion of diabetics from 4% to 25.5%. Concomitant CABG surgery increased from 36% to 49%. Overall mortality for isolated AVR was zero in the first 30 days and 1.6% in the next 11 months. For AVR and CABG, mortality was 3.75% and 9%, respectively. For octogenarians, mortality was zero and 5.9% for AVR and 4.76% and 14.29% for AVR and CABG at 30 days and in the next 11 months, respectively. CONCLUSIONS: Thirty-day mortality in all age groups remained low but was much higher in the short term after discharge from hospital, particularly in octogenarians and those with concomitant ischemic heart disease. This should inform the consent process (which traditionally concentrates on in-hospital mortality) and there should be greater awareness of the frailty and particular requirements of the elderly after discharge.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。