Abstract
Lyme disease (LD) is the most common vector-borne disease in the United States; however, it is very rare in Saudi Arabia. If left untreated, the disease can lead to neuroborreliosis, which can rarely present as Guillain-Barré-like syndrome. We propose the possible diagnosis of an unusual presentation of neuroborreliosis in a patient with a previous presumed diagnosis of Guillain-Barré syndrome (GBS) in Jeddah, Saudi Arabia. Early clinical suspicion and accurate testing can lead to proper diagnosis and case management. Cases of LD in Saudi Arabia are limited in the literature. The association between GBS and LD is very uncommon, although there are anecdotal reports in the literature. We would like to raise awareness, among clinicians, including primary care physicians regarding the possibility of LD in Jeddah, Saudi Arabia.