Abstract
OBJECTIVE: Integrating IoT technologies into the healthcare system has significantly raised the prospects for patient monitoring and disease prediction. However, the present-day models have failed to effectively encompass spatial-temporal data samples. METHODS: This paper presents a novel hybrid machine-learning model by amalgamating Convolutional Neural Networks (CNNs) with Long Short-Term Memory models (LSTMs) to boost prediction accuracy. Whereas the CNNs extract spatial features from medical images, the LSTMs model the temporal patterns of wearable sensor data. Such a configuration increases the prediction accuracy by 10% more than that achieved by the individual models. For better feature extraction, the proposed method implements Physiological Event Extraction (PEE), which is aimed at identifying important physiological events such as heart rate variability and respiratory changes from raw sensor data samples. RESULTS: This method helps render the features interpretable, providing another 15% improvement in prediction performance. Anomaly detection employed ensemble techniques that combined the Isolation Forest and One-Class SVM, reducing false positives by 20%, thus outperforming conventional approaches. It further enhanced the True Positive Rate (TPR) by 25% through using an online learning algorithm with Incremental Gradient Descent with Momentums. Robust statistical methods based on M-estimator theory had been integrated for the treatment of outliers and missing data, which helped in reducing bias in estimation by 30% and increasing the False Positive Rate (FPR) by 12%. CONCLUSION: All these enhancements constitute a major step towards improving the IoT healthcare data processing chain, thereby providing a trusted and accurate system for real-time health monitoring and anomaly detection. In this regard, the research also paves the way for designing next-gen IoT healthcare analytics and their actual clinical applications.