Case report: Surgical and clinical results in bilateral lenticonus due to Alport syndrome

病例报告:双侧晶状体圆锥症(Alport综合征)的手术及临床结果

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Abstract

Alport syndrome (AS) is a genetic disease characterized by hereditary nephritis, sensorineural hearing loss, and ocular anomalies. The most common ocular findings associated with AS include anterior lenticonus, retinal dot-fleck configuration, and corneal posterior polymorphism. Anterior lenticonus is 8 times more common in men with AS than in women. This case report evaluated the clinical and optical results obtained after phacoemulsification (PHACO) surgery and intraocular lens (IOL) implantation performed for bilateral anterior lenticonus due to AS. A 35-year-old male patient had complained of progressively decreasing vision for 10 years. The patient's ophthalmologic examination revealed bilateral anterior lenticonus and nuclear sclerosis. Continuous curvilinear capsulorhexis was applied in the anterior capsulorhexis method. Phacoemulsification surgery was performed using a high-viscoelastic material, starting the anterior capsulorhexis from the mid-periphery. The surgery was completed without anterior and posterior capsular rupture. Optimal postoperative refraction was achieved due to the IOL calculation performed using the traditional SRK-T formula. As a result, it has been shown that successful and uncomplicated results can be achieved with careful surgical technique and appropriate IOL selection in anterior lenticonus surgery due to AS.

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