T(1) Thermometry for Deep Brain Stimulation Applications: A Comparison between Rapid Gradient Echo Sequences

T(1)测温法在深部脑刺激应用中的比较:快速梯度回波序列的比较

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Abstract

BACKGROUND: T(1) thermometry is considered a straight method for the safety monitoring of patients with deep brain stimulation (DBS) electrodes against radiofrequency-induced heating during Magnetic Resonance Imaging (MRI), requiring different sequences and methods. OBJECTIVE: This study aimed to compare two T(1) thermometry methods and two low specific absorption rate (SAR) imaging sequences in terms of the output image quality. MATERIAL AND METHODS: In this experimental study, a gel phantom was prepared, resembling the brain tissue properties with a copper wire inside. Two types of rapid gradient echo sequences, namely radiofrequency-spoiled and balanced steady-state free precession (bSSFP) sequences, were used. T(1) thermometry was performed by either T(1)-weighted images with a high SAR sequence to increase heating around the wire or T(1) mapping methods. RESULTS: The balanced steady-state free precession (bSSFP) sequence provided higher image quality in terms of spatial resolution (1×1×1.5 mm(3) compared with 1×1×3 mm(3)) at a shorter acquisition time. The susceptibility artifact was also less pronounced for the bSSFP sequence compared with the radiofrequency-spoiled sequence. A temperature increase, of up to 8 ℃, was estimated using a high SAR sequence. The estimated change in temperature was reduced when using the T(1) mapping method. CONCLUSION: Heating induced during MRI of implanted electrodes could be estimated using high-resolution T(1) maps obtained from inversion recovery bSSFP sequence. Such a method gives a direct estimation of heating during the imaging sequence, which is highly desirable for safe MRI of DBS patients.

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