Abstract
AIM: The purpose of this study is to improve the precision of radiation treatment and sparing of organ-at-risk (OAR) in patients with thoracic esophageal cancer (EC) affecting the heart, lung, and spinal cord. To improve and personalize cancer treatment plans, it assesses the dosimetric benefits of coplanar RapidArc (RA(c)), hybrid arc (RA(Hyb)), and noncoplanar RapidArc (RA(nc)). MATERIALS AND METHODS: Fourteen patients with EC were chosen for our investigation from our hospital's database. RapidArc (RA) plan patients had already received treatment. Retrospectively, additional RA(nc) and RA(Hyb) plans were made with a prescription dose of 50.4 Gy in 28 fractions for the planning target volume (PTV). A prescription dose of 95% of PTV was used, so that three different treatment planning procedures could be compared. The cumulative dose-volume histogram was used to analyze the plan quality indices homogeneity index (HI), conformity index (CI), conformation number (CN) as well as the OARs doses to the lung, heart, and spinal cord. RESULTS: In comparison to RA(c) and RA(nc) techniques, the study indicated that RA(Hyb) plans significantly increased D95%, CI and HI; Dmax and CN did not differ substantially. In addition, compared to RA(c) (lung: 16.15 ± 0.03 Gy and heart: 23.91 ± 4.67 Gy) and RA(nc) (lung: 15.24 ± 0.03 Gy and heart 23.82 ± 5.10 Gy) plans, RA(Hyb) resulted in significantly lower mean lung doses (15.10 ± 0.03 Gy) and heart doses (21.33 ± 6.99 Gy). Moreover, the RA(Hyb) strategy showed a statistically significant (P < 0.05) lower average MU (452.7) than both the RA(c) (517.5) and RA(nc) (566.2) plans. CONCLUSION: The D95%, conformity, and homogeneity indices were better for hybrid arc plans compared to RA(c) and RA(nc) plans. They also successfully managed to reduce the lung and heart doses as well as the mean MU per fraction.