Incidental FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci

卵巢偶发性FOXL2突变成人颗粒细胞瘤伴卵泡膜细胞瘤样病灶

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Abstract

We report on the incidental finding of a FOXL2 mutated adult granulosa cell tumour of the ovary with thecoma-like foci, a rare entity recently described by Jennifer N. Stall and Robert H. Young in a series of sixteen cases in 2019, displaying features differing from conventional adult granulosa cell tumour. Our aim is to specify the morphologic and molecular particularities of this presumably underrecognized finding, with a short presentation of the typical clinical context. Awareness of this rare and challenging neoplasm with indeterminate clinical course is crucial in routine diagnostics.

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