Abstract
This symposium provided an extensive overview of emerging positron emission tomography (PET) tracers and targets for Alzheimer's disease (AD) and related dementias (ADRD), highlighting novel approaches for imaging neuroinflammation, neurotransmitter systems, mitochondrial dysfunction, and proteinopathies. Key developments included the harmonization of PET data across cohorts, new tau and alpha-synuclein tracers, and critical advancements in understanding neurodegenerative disease heterogeneity through integrated imaging, genetic, and pathological studies.