Inhibition of DDAH1, but not DDAH2, results in apoptosis of a human trophoblast cell line in response to TRAIL
抑制 DDAH1 而非 DDAH2 会导致人类滋养层细胞系因 TRAIL 而凋亡
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作者:B A Lumicisi, J E Cartwright, K Leslie, A E Wallace, G S Whitley
| 期刊: | Human Reproduction | 影响因子: | 6.000 |
| 时间: | 2015 | 起止号: | 2015 Aug;30(8):1813-9. |
| doi: | 10.1093/humrep/dev138 | 研究方向: | 免疫、细胞生物学 |
| 细胞类型: | 其它细胞 | 信号通路: | Apoptosis |
Methods
The effect of DDAH on trophoblast apoptosis was examined using siRNA and time-lapse microscopy. Changes in the expression of DDAH were followed by PCR and western blot analysis. Receptor expression was followed by flow cytometry. Main
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