Abstract
OBJECTIVE: The objective is to determinate the association between the degree of aortic valve calcification and the presence of paravalvular leakage (PVL) in Mexican patients who underwent transcatheter aortic valve replacement (TAVR). METHODS: We conducted a retrospective, analytic, cohort. Pooled data were retrospectively analyzed from the patient's files from January 2014 to July 2022. With a median follow-up of 6 months. RESULTS: We included 83 patients. 31 (37.3%) developed residual PVL. Several factors as male gender (men 58.1% versus women 41.9% p = 0.01), higher gradients previous TAVR (mean 57 mmHg in the group with versus mean 53 mmHg in the group without PVL, p = 0.01), bigger annulus diameters and perimeters as well as reduce left ventricular ejection fraction and a degree of aortic regurgitation previous TAVR were present more frequently in the group of residual PVL. Aortic valve calcification was the only predictor after the bivariate and multivariate analysis that showed an association with the presence of PVL after TAVR. The calculated cut-off value of calcium score was 2970 Agatston units, with a sensitivity of 70% and a specificity of 60% as a predictor for PVL. CONCLUSIONS: The results are consistent with the previous data and there are no greater differences in the Mexican population. The severity of the aortic valve calcification is an independent predictor of PVL in patients who underwent TAVR.