Mimicking Alveolar Lung Structures with Lattice Designs

利用晶格设计模拟肺泡结构

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Abstract

Advances in additive manufacturing (AM) have revolutionized various sectors, including aerospace engineering, where the use of lattice structures has enabled the development of lightweight high-performance components with optimized mechanical properties. Building on these engineering principles, this study explores the application of aerospace-derived lattice design strategies to the biomedical field, specifically for the replication of human lung alveolar structures. The objective is to create anatomically accurate 3D-printed lung models suitable for surgical planning. Finite element analyses have been conducted using a CAD model of adult lungs, including the application of lattice structures generated through nTopology software, to evaluate the elasticity and density, critical for simulating lung mechanics. A preliminary prototype has been produced using stereolithography and flexible resin, showing the potential for realistic tactile feedback.

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