Abstract
Anadara kagoshimensis is a bivalve inhabiting coastal seafloors and has long been commercially harvested as a fishery resource. In Ariake Bay, a major production area for A. kagoshimensis in Japan, the catch has significantly declined due to marine environmental degradation, including seasonal oxygen depletion in bottom waters. This article presents the transcriptome dataset of gill tissues from A. kagoshimensis under anoxic and normoxic conditions. Anoxic treatment resulted in 894 upregulated and 903 downregulated deferentially expressed genes (P (adj) < 0.05). The expression of HIF-1α, a key regulator of the hypoxia responses, and genes associated with anaerobic metabolism was upregulated, while genes related to aerobic metabolism and hemoglobin expression showed a notable decrease. These RNA-seq data offer valuable insights into the adaptation mechanisms of A. kagoshimensis to anoxic environments and are accessible from the National Center for Biotechnology Information (NCBI) database under BioProject accession number PRJDB19614.