Abstract
Here, we report the draft genome sequence data of two multidrug-resistant (MDR) Staphylococcus haemolyticus strains, SAC2 and SAC7, isolated from clinical samples from Dhaka, Bangladesh. The sequence raw read files were generated using Ion Torrent Sequencing Technology using the genomic DNA from the pure culture of the strains. These two Bangladeshi S. haemolyticus strains had an average genome size of 2.49 million base pairs with a GC content of 32.6 % and an average of 1783 coding sequences. We conducted genomic studies using bioinformatics tools focusing on resistance genes, virulence factors, and toxin-antitoxin systems. A phylogenomic study with S. haemolyticus strains isolated worldwide revealed that these two Bangladeshi strains are in different nodes but clustered together. The data can be used as a starting point for understanding the genomic content, epidemiology, and evolution of S. haemolyticus in Bangladesh. The genome sequence data of SAC2 and SAC7 strains have been deposited in the NCBI database under BioSample accession numbers SAMN35731443 and SAMN35731649, respectively.