Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice
全面表征肝细胞衍生的细胞外囊泡,确定酒精性肝炎小鼠中基于 miRNA 的肝星状细胞和基于 DAMP 的肝巨噬细胞 IL-1β 和 IL-17 上调的直接调控
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作者:Akiko Eguchi, Rui Yan, Stephanie Q Pan, Raymond Wu, Jihoon Kim, Yibu Chen, Charles Ansong, Richard D Smith, Mina Tempaku, Lucila Ohno-Machado, Yoshiyuki Takei, Ariel E Feldstein, Hidekazu Tsukamoto